Hard Bioinformatics Quiz: Master Genomic Algorithms
Assess your proficiency in computational biology with five demanding multiple‑choice items.
Quiz Questions
Answer all questions below and test your knowledge.
- 1
Which data structure enables rapid substring searches during short-read alignment by transforming the reference genome?
- 2
In a profile Hidden Markov Model for protein families, which state type emits residues with position‑specific probabilities?
- 3
What is the asymptotic time complexity for constructing a de Bruijn graph from N reads of length L, assuming k‑mer extraction dominates?
- 4
DESeq2 estimates differential expression by modeling count data with which statistical distribution?
- 5
The Global Distance Test total score (GDT_TS) used to assess predicted protein structures ranges between what values?
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